Exomphalos;
Enterococcus faecium;
high level aminoglycoside resistance;
D O I:
10.4103/1755-6783.105159
中图分类号:
R188.11 [热带医学];
学科分类号:
摘要:
Exomphalos minor is one among uncommon disorders of the umbilical region. Here, we report a fatal case of exomphalos minor with enterococcal septicemia. A male baby, born with exomphalos minor, developed clinical features of septicemia on the fourth postnatal day. Blood samples were collected by venepuncture from two sites for culture. Enterococcus faecium was isolated from both the blood samples. The swabs collected from the site of exomphalos also yielded growth of Enterococcus faecium, confirming the source of infection. The antibiogram with Minimum Inhibitory Concentrations (MIC) for various antibiotics was done for isolates from all three sites, which was similar. The isolate was resistant to multiple antibiotics with high level aminoglycoside resistance. The baby was treated with antibiotics and other supportive measures. However, the baby succumbed to the septicemia. As per our knowledge, this is the first reported case of fatal septicemia by multidrug-resistant Enterococcus faecium in a case of exomphalos minor.
机构:
Univ Manchester, Manchester Interdisciplinary Bioctr, Manchester M1 7DN, Lancs, England
Univ Manchester, Fac Life Sci, Manchester M1 7DN, Lancs, EnglandUniv Manchester, Manchester Interdisciplinary Bioctr, Manchester M1 7DN, Lancs, England
Derome, Andrew
Hoischen, Christian
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Fritz Lipmann Inst, Leiden Inst Age Res, D-07745 Jena, GermanyUniv Manchester, Manchester Interdisciplinary Bioctr, Manchester M1 7DN, Lancs, England
Hoischen, Christian
Bussiek, Malte
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Univ Twente, Biophys Engn Grp, NL-7500 AE Enschede, NetherlandsUniv Manchester, Manchester Interdisciplinary Bioctr, Manchester M1 7DN, Lancs, England
Bussiek, Malte
Grady, Ruth
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Univ Manchester, Fac Life Sci, Manchester M1 7DN, Lancs, EnglandUniv Manchester, Manchester Interdisciplinary Bioctr, Manchester M1 7DN, Lancs, England
Grady, Ruth
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Adamczyk, Malgorzata
Kedzierska, Barbara
论文数: 0引用数: 0
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Univ Manchester, Manchester Interdisciplinary Bioctr, Manchester M1 7DN, Lancs, England
Univ Manchester, Fac Life Sci, Manchester M1 7DN, Lancs, EnglandUniv Manchester, Manchester Interdisciplinary Bioctr, Manchester M1 7DN, Lancs, England
Kedzierska, Barbara
Diekmann, Stephan
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机构:
Fritz Lipmann Inst, Leiden Inst Age Res, D-07745 Jena, GermanyUniv Manchester, Manchester Interdisciplinary Bioctr, Manchester M1 7DN, Lancs, England
机构:
Pfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USAPfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USA
Kodali, Srinivas
Vinogradov, Evgeny
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CNR, Ottawa, ON K1A 0R6, CanadaPfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USA
Vinogradov, Evgeny
Lin, Fiona
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Pfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USAPfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USA
Lin, Fiona
Khoury, Nancy
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Pfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USAPfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USA
Khoury, Nancy
Hao, Li
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Pfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USAPfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USA
Hao, Li
Pavliak, Vilo
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h-index: 0
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Pfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USAPfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USA
Pavliak, Vilo
Jones, C. Hal
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Pfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USAPfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USA
Jones, C. Hal
Laverde, Diana
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机构:
Univ Hosp, Div Infect Dis, Dept Med, D-79106 Freiburg, GermanyPfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USA
Laverde, Diana
Huebner, Johannes
论文数: 0引用数: 0
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机构:
Univ Hosp, Div Infect Dis, Dept Med, D-79106 Freiburg, Germany
Univ Munich, Dr von Hauner Childrens Hosp, Dept Pediat, D-80338 Munich, GermanyPfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USA
Huebner, Johannes
Jansen, Kathrin U.
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Pfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USAPfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USA
Jansen, Kathrin U.
Anderson, Annaliesa S.
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Pfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USAPfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USA
Anderson, Annaliesa S.
Donald, Robert G. K.
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Pfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USAPfizer Vaccine Res & Early Dev, Pearl River, NY 10654 USA
机构:
Allatorvostud Egyet, Patol Tanszek, Istvan Utca 2, H-1078 Budapest, HungaryAllatorvostud Egyet, Patol Tanszek, Istvan Utca 2, H-1078 Budapest, Hungary
Horvath, David Geza
Toth, Gergely
论文数: 0引用数: 0
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Allatorvostud Egyet, Jarvanytani & Mikrobiol Tanszek, Budapest, HungaryAllatorvostud Egyet, Patol Tanszek, Istvan Utca 2, H-1078 Budapest, Hungary
Toth, Gergely
Lencse, Zsofia
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机构:
PrimaVet Kisallat Rendeloint, Budapest, HungaryAllatorvostud Egyet, Patol Tanszek, Istvan Utca 2, H-1078 Budapest, Hungary
Lencse, Zsofia
Balka, Gyula
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机构:
Allatorvostud Egyet, Patol Tanszek, Istvan Utca 2, H-1078 Budapest, HungaryAllatorvostud Egyet, Patol Tanszek, Istvan Utca 2, H-1078 Budapest, Hungary
机构:
Univ Sao Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmaceut Ribeirao Preto, Sao Paulo, BrazilUniv Sao Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmaceut Ribeirao Preto, Sao Paulo, Brazil
dos Santos, L. D. R.
Furlan, J. P. R.
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机构:
Univ Sao Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmaceut Ribeirao Preto, Sao Paulo, BrazilUniv Sao Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmaceut Ribeirao Preto, Sao Paulo, Brazil
Furlan, J. P. R.
Gallo, I. F. L.
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Univ Sao Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmaceut Ribeirao Preto, Sao Paulo, BrazilUniv Sao Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmaceut Ribeirao Preto, Sao Paulo, Brazil
Gallo, I. F. L.
Ramos, M. S.
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机构:
Univ Sao Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmaceut Ribeirao Preto, Sao Paulo, BrazilUniv Sao Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmaceut Ribeirao Preto, Sao Paulo, Brazil
Ramos, M. S.
Savazzi, E. A.
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机构:
Companhia Ambiental Estado Sao Paulo CETESB, Ribeirao Preto, BrazilUniv Sao Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmaceut Ribeirao Preto, Sao Paulo, Brazil
Savazzi, E. A.
Stehling, E. G.
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Univ Sao Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmaceut Ribeirao Preto, Sao Paulo, BrazilUniv Sao Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmaceut Ribeirao Preto, Sao Paulo, Brazil