A PRACTICAL AND EFFICIENT SYNTHESIS OF THE ZIEGLER KEY INTERMEDIATE FOR THE SYNTHESIS OF FORSKOLIN

被引：5

作者：

COLOMBO, MI ^{[1
]}

SOMOZA, C ^{[1
]}

ZINCZUK, J ^{[1
]}

BACIGALUPPO, JA ^{[1
]}

RUVEDA, EA ^{[1
]}

机构：

[1] UNIV NACL ROSARIO,CONSEJO NACL INVEST CIENT & TECN,FAC CIENCIAS BIOQUIM & FARMACEUT,RA-2000 ROSARIO,ARGENTINA

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 01期

关键词：

D O I：

10.1016/S0040-4039(00)94328-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Ziegler intermediate 2, previously used in three total syntheses of forskolin (1), has been synthesized efficiently from enone 3. The key transformation of this sequence is the early and stereoselecrive introduction of the C-6, C-7 oxygen functional groups present in the natural product. © 1990.

引用

页码：39 / 42

页数：4

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