4-YEAR STABILITY OF DER-P-I IN-HOUSE DUST UNDER SIMULATED DOMESTIC CONDITIONS IN-VITRO

被引：19
|
作者：
KORT, HSM
KNIEST, FM
机构：
[1] Interuniversity Task Group "Home and Health, Eindhoven University of Technology, Eindhoven
[2] Allergopharma Joachim Ganzer KG, Research-Prevention (F-Praev) Division, Hamburg
来源：
ALLERGY | 1994年 / 49卷 / 02期
关键词：
AVOIDANCE PROGRAMS; DER-P-I; HOUSE DUST; HOUSE-DUST MITES;
D O I：
10.1111/j.1398-9995.1994.tb00813.x
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
For almost 4 years, the stability of Der p I was assessed by RAST inhibition in house-dust samples incubated under simulated domestic conditions (5 or 25-degrees-C and 75% relative humidity). Der p I concentrations were determined before heating dust samples at 60-degrees-C to kill the mites, and at 0, 6, 14, 21, and 47 months after heating. Heating at 60-degrees-C for 24 h caused no significant change in Der p I concentration. After a 47-month incubation under simulated domestic conditions, reduction of Der p I was still not obvious. It is concluded that even after extermination of mites, home textiles remain allergen reservoirs for an extended period of time. Avoidance schemes should take this into account.
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页码：131 / 133
页数：3
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