PLATELET MONOAMINE OXIDASE-B ACTIVITY IN PARKINSONIAN-PATIENTS

被引：23
|
作者：
BONUCCELLI, U
PICCINI, P
DELDOTTO, P
PACIFICI, GM
CORSINI, GU
MURATORIO, A
机构：
[1] UNIV PISA,INST GEN PATHOL,I-56100 PISA,ITALY
[2] UNIV PISA,INST PHARMACOL,I-56100 PISA,ITALY
来源：
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1990年 / 53卷 / 10期
关键词：
D O I：
10.1136/jnnp.53.10.854
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Monoamine oxidase B (MAO B) plays a pivotal role in N-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine (MPTP) induced Parkinsonism. An increased MAO B activity in platelets of patients with idiopathic Parkinson's disease (PD) is reported in this study. The possibility that high MAO B activity may represent a trait of vulnerability for PD by enhancing the neurotoxic effects of environmental compounds is discussed.
引用
收藏
页码：854 / 855
页数：2
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