OPTICAL PURITY DETERMINATION OF THYROXINE ENANTIOMERS IN BULK MATERIALS BY CHIRAL THIN-LAYER CHROMATOGRAPHY

被引：9
|
作者：
ABOULENEIN, HY
SERIGNESE, V
机构：
[1] Bioanalytical and Drug development Laboratory, Biological and Medical Research Department (MBC-03), King Faisal Specialist Hospital and Research Centre, Riyadh, 11211
来源：
BIOMEDICAL CHROMATOGRAPHY | 1994年 / 8卷 / 06期
关键词：
D O I：
10.1002/bmc.1130080616
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
L-thyroxine and D-thyroxine were separated on ligand exchange chiral thin layer chromatographic plates, using a solvent system consisting of acetonitrile:methanol:water 60:15:15 v/v, at a wavelength of 254 nm. The methodology, chiral recognition mechanism(s) involved and its application are discussed.
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页码：317 / 318
页数：2
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