CHANGES IN HUMAN AND RAT UTERINE PHOSPHOETHANOLAMINE AND TAURINE WITH PREGNANCY AND PARTURITION

被引：12
|
作者：
PHOENIX, J [1 ]
WRAY, S [1 ]
机构：
[1] UNIV LIVERPOOL,PHYSIOL LAB,LIVERPOOL L69 3BX,ENGLAND
来源：
EXPERIMENTAL PHYSIOLOGY | 1994年 / 79卷 / 04期
基金：
英国惠康基金;
关键词：
D O I：
10.1113/expphysiol.1994.sp003794
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Phosphoethanolamine and taurine have been identified in uterine extracts from rat and, for the first time, human tissue. The concentration of phosphoethanolamine [PEtn] determined by HPLC and P-31 NMR spectroscopy, increased markedly (40%) within the first 6-12 h following parturition in rats, suggesting a role in involution. It appears that changes in [PEtn] account for the changes in the NMR phosphomonoester peak previously reported. A significant fall in [PEtn] was found in the human myometrium with pregnancy. Taurine was found in high concentrations in the rat and human uterus but decreased with pregnancy. The possible functional significance of these changes is discussed.
引用
收藏
页码：601 / 604
页数：4
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