EFFICIENT SYNTHESIS OF 2'-AMINO-2'-DEOXYPYRIMIDINE 5'-TRIPHOSPHATES

被引：25
|
作者：
MCGEE, DPC [1 ]
VARGEESE, C [1 ]
ZHAI, YS [1 ]
KIRSCHENHEUTER, GP [1 ]
SETTLE, A [1 ]
SIEDEM, CR [1 ]
PIEKEN, WA [1 ]
机构：
[1] NEXAGEN INC,BOULDER,CO 80301
来源：
NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 06期
关键词：
D O I：
10.1080/15257779508010694
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The synthesis of 2'-amino-2'-deoxypyrimidine 5'-triphosphates is described. The 2'-amino-2'-deoxyuridine 5'-triphosphate is obtained from uridine in four steps with 25% overall yield. The 2'-amino-2'-deoxycytidine 5'-triphosphate is obtained from uridine in seven steps with 13% overall yield.
引用
收藏
页码：1329 / 1339
页数：11
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