COPPER COMPLEXES OF AMINOTHIOPHENE SCHIFF BASES AS ANTIMICROBIAL AGENTS: SYNTHESIS, STRUCTURAL CHARACTERIZATION, ANTIMICROBIAL AND ANTITUBERCULAR ACTIVITY EVALUATION

被引：0

作者：

More, Ganesh ^{[1
]}

Bootwala, Sakina ^{[1
]}

Patil, Sujata ^{[2
]}

机构：

[1] Wilson Coll, Dept Chem, Bombay 400007, Maharashtra, India

[2] Wilson Coll, Dept Phys, Bombay 400007, Maharashtra, India

来源：

HETEROCYCLIC LETTERS | 2018年 / 8卷 / 02期

关键词：

Copper complex; Uropathogens; Multidrug-resistant; Schiff bases; H37Rv;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Series of potentially tridentate Schiff bases (3a-d) were derived from condensation of ethyl 2-amino-5,6-dihydro-4H-cyclopenta[b] thiophene-3-carboxylate (I) with o-hydroxyl aldehyde derivative (2a-d) which formed Cu(II) complexes in 1: 1 molar ratio. All the complexes were characterized by elemental analysis, FTIR, UV-Visible and ESR spectroscopy, XRD, magnetic susceptibility and molar conductance technique. According to spectroscopic and magnetic moment data, the monobasic tridentate ligand forms square planar complexes with Cu(II) metal ions. Metal complexes exhibited pronounced activity against gram-negative ESBL and MBL bacterial strains compared to the ligands. In addition, metal complexes displayed good antitubercular activity against M. tuberculosis (H37Rv strain).

引用

页码：345 / 357

页数：13

共 50 条

[1] Synthesis, characterization and in vitro antimicrobial activity of some new Schiff bases and their complexes
Hossein Naeimi
Zahra Sadat Nazifi
Seyedeh Matin Amininezhad
Mehdi Amouheidari
The Journal of Antibiotics, 2013, 66 : 687 - 689
[2] Synthesis, Characterization and In vitro Antitubercular and Antimicrobial Activities of new Aminothiophene Schiff Bases and their Co(II), Ni(II), Cu(II) and Zn(II) Metal Complexes
More, Ganesh
Bootwala, Sakina
Shenoy, Sushma
Mascarenhas, Joyline
Aruna, K.
ORIENTAL JOURNAL OF CHEMISTRY, 2018, 34 (02) : 800 - 812
[3] Synthesis, characterization and in vitro antimicrobial activity of some new Schiff bases and their complexes
Naeimi, Hossein
Nazifi, Zahra Sadat
Amininezhad, Seyedeh Matin
Amouheidari, Mehdi
JOURNAL OF ANTIBIOTICS, 2013, 66 (11): : 687 - 689
[4] Antimicrobial salicylaldehyde Schiff bases: Synthesis, characterization and evaluation
Muhammad, Hafiz
Sharif, Adeel
Ahmed, Dildar
Mir, Hira
PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, 28 (02) : 449 - 455
[5] Synthesis, characterization and antimicrobial studies of novel Schiff bases and their complexes
Jacob, Biju
Datta, Riya
INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY, 2021, 60 (04): : 538 - 544
[6] Synthesis, spectroscopic characterization and antimicrobial activity evaluation of new tridentate Schiff bases and their Co(II) complexes
More, Ganesh
Raut, Darshana
Aruna, K.
Bootwala, Sakina
JOURNAL OF SAUDI CHEMICAL SOCIETY, 2017, 21 (08) : 954 - 964
[7] Synthesis, characterisation and antimicrobial activity of copper(II) and iron(II) complexes with some Schiff bases
Chaudhary, Ritu Rani
Saxena, P. N.
ORIENTAL JOURNAL OF CHEMISTRY, 2009, 25 (03) : 529 - 534
[8] Synthesis and antimicrobial activity of copper-, cobalt- and nickel(II) complexes with Schiff bases
Jadegoud, Y
Ijare, OB
Mallikarjuna, NN
Angadi, SD
Mruthyunjayaswamy, BHM
JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2002, 79 (12) : 921 - 924
[9] SYNTHESIS, STRUCTURAL CHARACTERIZATION AND ANTIMICROBIAL STUDIES OF NOVEL SCHIFF BASE COPPER(II) COMPLEXES
Raman, N.
Joseph, J.
Sakthivel, A.
Jeyamurugan, R.
JOURNAL OF THE CHILEAN CHEMICAL SOCIETY, 2009, 54 (04): : 354 - 357
[10] Synthesis, characterization and antimicrobial studies of some metal complexes with Schiff bases
Pandhare, G. R.
Gholap, S. S.
ASIAN JOURNAL OF CHEMISTRY, 2008, 20 (07) : 5536 - 5540

← 1 2 3 4 5 →