SYNTHESIS OF TRIPEPTIDE GLYCYL-L-LEUCYL-L-PHENYLALANINE AND ITS ANALOGS

被引：0

作者：

ESIPOVA, OV

EREMIN, SV

ZVONKOVA, EN

机构：

来源：

BIOORGANICHESKAYA KHIMIYA | 1991年 / 17卷 / 08期

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Peptide Gly-L-Leu-L-Phe and its derivatives were synthesized by the C-end elongation utilizing DCC/HOBT technique and by enzymatic route with the help of papain using esters of N-benzyloxycarbonyl-glycine and -L-leucine as acyl donors have been suggested. The chemical, similarly to the enzymatic, synthesis was not accompanied by racemization. Conditions for HPLC separation and preparative isolation of the enzymatic reaction products were developed.

引用

页码：1077 / 1085

页数：9

共 50 条

[1] CRYSTAL-STRUCTURE OF L-GLYCYL-L-LEUCYL-L-PHENYLALANINE HEMIHYDRATE
DELETTRE, J
BERTHOU, J
LIFCHITZ, A
JOLLES, P
[J]. ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1988, 44 : 902 - 904
[2] PEPTIDE KINETICS .7. ACID-CATALYZED HYDROLYSIS OF GLYCYL-L-LEUCYL-L-LEUCINE L-LEUCYL-L-LEUCINE GLYCYL-L-PHENYLALANYL-L-PHENYLALANINE AND L-PHENYLALANYL-L-PHENYLALANINE
LONG, DA
TRUSCOTT, TG
[J]. TRANSACTIONS OF THE FARADAY SOCIETY, 1968, 64 (547P): : 1866 - &
[3] SYNTHESIS OF CYCLO(-L-LEUCYL-L-LYSYL-GLYCYL-)2 AND ITS HYDROLYSIS BY TRYPSIN
KOSUI, N
KATO, T
IZUMIYA, N
[J]. BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1978, 51 (12) : 3665 - 3666
[4] EFFECT OF N-FORMYL-L-METHIONYL-L-LEUCYL-L-PHENYLALANINE AND ITS ANALOGS ON BLOOD-PRESSURE
SAITO, H
MATSUO, M
NAMINOHIRA, S
SAKAI, T
KITAGAWA, H
HIRATA, AA
[J]. JOURNAL OF PHARMACOBIO-DYNAMICS, 1983, 6 (02): : 141 - 144
[5] CRYSTAL-STRUCTURE OF A TRIPEPTIDE, GLYCYL-D, L-LEUCYL-L, D-ALANINE
JAYASHREE, V
RAJAN, SS
SUBRAMANIAN, E
[J]. CURRENT SCIENCE, 1993, 65 (01): : 77 - 79
[6] SYNTHESIS OF L-TYROSYL-D-TRYPTOPHANYL-GLYCYL-L-LEUCYL-L-METHIONINE AMIDE
LIPKOWSKI, AW
MAJEWSKI, T
DRABAREK, S
[J]. POLISH JOURNAL OF CHEMISTRY, 1979, 53 (12) : 2459 - 2463
[7] N-BENZYLOXYCARBONYL-GLYCYL-L-PROLYL-L-LEUCYL-GLYCYL-L-PROLINE DIHYDRATE
BANDO, S
TANAKA, N
ASHIDA, T
KAKUDO, M
[J]. ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE, 1978, 34 (NOV): : 3447 - 3449
[8] SYNTHESIS AND STUDY OF PROPERTIES OF PENTIDES, CONTAINING PROLINE AND ORNITHINE RADICALS .8. SYNTHESIS OF GLYCYL-L-LEUCYL-L-ORNITHYL-L-PHENYLALANYL-L-PROLYL-L-ORNITHYL-D-PHENYLALANYL-L-PROPYL-L-ORNITHYL-GLYCYL-D-LEUCYL-L-ORNITHINE AND GLYCYL-D-LEUCYL-D,L-ORNITHYL-L-PHENYLALANYL-L-PROLYL-L-ORNITHYL-GLYCYL-D-LEUCYL-L-ORNITHYL-D-PHENYLALANYL-L-PROLYL-L-ORNITHINE DODECAPEPTIDESY
PODDUBNAYA, NA
[J]. ZHURNAL OBSHCHEI KHIMII, 1973, 43 (04): : 917 - 921
[9] SYNTHESIS OF GLYCYL-L-PROLYL-L-LEUCYL-[C-14(U)] GLYCYL-L-PROLINE AS A SUBSTRATE FOR COLLAGENASE
LAMTHANH, H
HEINDL, MC
FERMANDJIAN, S
[J]. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 1979, 16 (06): : 843 - 849
[10] SYNTHESIS AND STUDY OF PEPTIDES WITH PROLINE AND ORNITHINE RADICALS .7. SYNTHESIS OF NONAPEPTIDES OF GLYCYL-D-LEUCYL-L-ORNITHYL-D-PHENYLALANYL-L-PROLYL-L-ORNITHYL-GLYCYL-D-LEUCYL-L-ORNITHINE AND D-PHENYLALANYL-L-PROLYL-D, L-ORNITHYL-L-PHENYLALANYL-L-PROLYL-L-ORNITHYL-GLYCYL-D-LEUCYL-L-ORNITHINE
PODDUBNA.NA
KRASNOBR.NY
[J]. ZHURNAL OBSHCHEI KHIMII, 1973, 43 (01): : 199 - 202

← 1 2 3 4 5 →