EFFECTS OF CHOLESTEROL LOADING OF MOUSE MACROPHAGES ON CARNITINE PALMITOYLTRANSFERASE ACTIVITY AND SENSITIVITY TO INHIBITION BY MALONYL-COA

被引:9
|
作者
KASHFI, K
DORY, L
COOK, GA
机构
[1] Department of Pharmacology, College of Medicine, The University of Tennessee, Memphis, TN 38163
关键词
D O I
10.1016/0006-291X(91)90655-Q
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Scavenger receptor-mediated uptake of acetylated low density lipoprotein-derived cholesterol by peritoneal mouse macrophages resulted in decreased activity of the malonyl-CoA inhibitable carnitine palmitoyltransferase and a decrease in the sensitivity of this enzyme to inhibition by malonyl-CoA. © 1991.
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页码:1121 / 1126
页数:6
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