Elimination of platelet dysfunctions in newborn calves with functional digestive disorders

The occurrence of functional disorders of the digestive system in newborn calves often leads to deterioration of the blood rheology due to the activation of platelets against the background of the activation of lipid peroxidation and an increase in the blood content of middle molecules. Platelet dysfunctions in them contribute to the deterioration of microcirculation in the organs of animals due to active intravascular thrombus formation. In newborn calves with functional digestive disorders, an increase in platelet aggregation functions was found in vitro and in vivo. These disorders are based on deep changes in the lipid composition of platelet membranes, an increase in the content of medium molecules in the plasma and blood plates, the activation of lipid peroxidation in them, the intensification of thromboxane formation in blood plates, which is developing on this background. Activation of thronnboplastin formation is the leading cause of increased blood coagulation in newborn calves with functional disorders of the digestion. It was possible to identify the possibility of correcting disorders of platelet hemostasis with the help of a complex from Phosphopag and Ekos, which can reduce the level of medium molecules in the body and correct lipid peroxidation. In addition, the use of Phosphopagus and Ekos in newborn calves with functional digestive disorders reduces the severity of platelet hemostasis disorders by approaching the rate of increased platelet aggregation and intravascular activity of platelets.