NEUROTRANSMITTERS, NEUROPEPTIDES AND EATING BEHAVIOR

A number of monoamines and neuropeptides are involved in the control of eating behavior. In the central nervous system, the medial and lateral hypothalamus (connected with cortical and limbic systems as well as with the peripheral endocrine and autonomic nervous systems) integrates informations concerning the nutritional and biopsychological status and control feeding behavior and weight regulation. Modern neurobiological techniques have generated a great range of information on the role of monoamines and neuropeptides in controlling food intake. Substances such as norepinephrine, opioids, neuropeptide Y are potent stimulators of investive behavior. Serotonin, cholecystokinin, and corticotropin-releasing factor inhibit food intake. The physiological influence of these substances is undergoing evaluation.