Genetics in Age-Related Macular Degeneration: Current Research and Implications for Future Treatment

被引：1
|
作者：
Broadhead, Geoffrey Kenneth [1 ,2 ]
Chang, Andrew [1 ,2 ,3 ]
McCluskey, Peter [2 ,3 ]
机构：
[1] Sydney Retina Clin & Day Surg, Level 13,Pk House,187 Macquarie St, Sydney, NSW 2000, Australia
[2] Univ Sydney, Save Sight Inst, Sydney, NSW, Australia
[3] Sydney Eye Hosp, Sydney, NSW, Australia
来源：
ASIA-PACIFIC JOURNAL OF OPHTHALMOLOGY | 2012年 / 1卷 / 05期
关键词：
age-related macular degeneration; genetics; pharmacogenetics;
D O I：
10.1097/APO.0b013e31826e1d4a
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Age-related macular degeneration (AMD) remains a leading cause of visual loss in the developed world, and genetic factors are known risks for disease development, as well as affecting response to therapy. Here, we review genetic factors associated with AMD and the influence of genetics on the understanding of AMD pathogenesis. The potential role of genetics in assisting in the management of AMD and future research avenues are also discussed.
引用
收藏
页码：312 / 318
页数：7
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