The pharmacology of infection after total joint arthroplasty

被引：4
|
作者：
Hartman, Curtis [1 ]
Hewlett, Angela [1 ]
Garvin, Kevin [1 ]
机构：
[1] Univ Nebraska, Med Ctr, Dept Orthopaed, Omaha, NE USA
来源：
CURRENT ORTHOPAEDIC PRACTICE | 2012年 / 23卷 / 06期
关键词：
antibiotic therapy; hip arthroplasty; knee arthroplasty; prosthetic joint infection;
D O I：
10.1097/BCO.0b013e318271bfdc
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Choosing appropriate antimicrobial therapy for prosthetic joint infections is a multifactorial and often complicated process. Factors that influence antimicrobial decision-making include pharmacodynamics, choice of surgical management, patient tolerance and allergy, financial considerations, and convenience of dosing. Recommendations regarding antimicrobial therapy for prosthetic joint infections vary greatly, and studies to define optimal therapy are lacking. Over the past 10 years, most of the literature on the treatment of prosthetic joint infection has focused on the utility of combination antimicrobial therapy and newer agents to combat multidrug-resistant pathogens.
引用
收藏
页码：529 / 532
页数：4
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