VITAMIN D AND ITS ROLE IN DERMATOLOGY: A REVIEW OF LITERATURE

被引：3

作者：

Sharma, Rohini ^{[1
]}

Abrol, Sameer ^{[2
]}

Badgal, Amit ^{[3
]}

Chowdhary, Shokat ^{[2
]}

机构：

[1] Govt Gandhinagar Hosp, Jammu, Jammu Kashmir, India

[2] GMC Jammu, Dept Med, Jammu Kashmir, India

[3] MMMCH, Dept Med, Solan, India

来源：

JOURNAL OF EVOLUTION OF MEDICAL AND DENTAL SCIENCES-JEMDS | 2015年 / 4卷 / 10期

关键词：

Vitamin D; calcitriol; anti-inflammatory; anti-proliferative;

D O I：

10.14260/jemds/2015/238

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Vitamin D is a fat-soluble steroid hormone that is crucial for human health. Since long the role of epidermal keratinocytes in the UVB-induced photochemical conversion of 7-dehydrocholesterol to vitamin D3 is known, and also for the enzymatically controlled hydroxylation of the photolysis product. This whole process results in the formation of the biologically active final product 1, 25-(OH)(2)D-3 (Calcitriol). Moreover recently various research articles have shown benefits of calcitriol and various other vitamin D analogues having a therapeutic role in various dermatologic conditions like psoriasis, atopic dermatitis, acne, vitiligo owing to its anti-inflammatory, antiproliferative action. The present review shows a summary of role of vitamin D in dermatologic perspective.

引用

页码：1689 / 1693

页数：5

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