Emerging roles of transcriptional programs in autophagy regulation

被引:21
|
作者
Sakamaki, Jun-Ichi [1 ]
Long, Jaclyn S. [1 ]
New, Maria [2 ]
Van Acker, Tim [2 ]
Tooze, Sharon A. [2 ]
Ryan, Kevin M. [1 ]
机构
[1] Canc Res UK Beatson Inst, Garscube Estate,Switchback Rd, Glasgow G61 1BD, Lanark, Scotland
[2] Francis Crick Inst, Mol Cell Biol Autophagy, London, England
来源
TRANSCRIPTION-AUSTIN | 2018年 / 9卷 / 02期
关键词
autophagy; BRD4; histone; lysosome; modification; TFEB; transcriptional regulation of autophagy;
D O I
10.1080/21541264.2017.1372045
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Autophagy is an essential cellular process that degrades cytoplasmic organelles and components. Precise control of autophagic activity is achieved by context-dependent signaling pathways. Recent studies have highlighted the involvement of transcriptional programs during autophagic responses to various signals. Here, we summarize the current understanding of the transcriptional regulation of autophagy.
引用
收藏
页码:131 / 136
页数:6
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