SCREENING AND PHYTOCHEMICAL ANALYSIS OF PHARMACOLOGICALLY ACTIVE COMPOUNDS FROM Abutilon Indicum and Phyllanthus Niruri AND ASSESSING THEIR IN VITRO ANTI MICROBIAL ACTIVITY AGAINST PATHOGENS

In the present investigation, the evaluation of anti-bacterial activity of Abutilon indicum and Phylanthus niruri has been carried out against human pathogenic microbes by disc diffusion agar method. The shade dried and powdered leaves were used for the extraction with different solvents. Thin Layer Chromatography profiles and phyto chemical screening were carried out for these extracts. The antagonistic activities of the extracts were tested against human pathogens. The results were tabulated and discussed with the related studies reported earlier. It is seen that the ethyl acetate extract of the leaves showed significant (0.7cm) anti bacterial activity when compared to the standard tetracycline against selected gram positive and gram negative bacteria.