Bacterial contamination of platelet concentrates: pathogen detection and inactivation methods

被引：17
|
作者：
Vedy, Dana [1 ]
Robert, Daniel [1 ]
Gasparini, Danielle [1 ]
Canellini, Giorgia [1 ]
Waldvogel, Sophie [1 ]
Tissot, Jean-Daniel [1 ]
机构：
[1] Serv Reg Vaudois Transfus Sanguine, Lausanne, Switzerland
来源：
HEMATOLOGY REPORTS | 2009年 / 1卷 / 01期
关键词：
D O I：
10.4081/hr.2009.e5
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Whereas the reduction of transfusion related viral transmission has been a priority during the last decade, bacterial infection transmitted by transfusion still remains associated to a high morbidity and mortality, and constitutes the most frequent infectious risk of transfusion. This problem especially concerns platelet concentrates because of their favorable bacterial growth conditions. This review gives an overview of platelet transfusion-related bacterial contamination as well as on the different strategies to reduce this problem by using either bacterial detection or inactivation methods.
引用
收藏
页码：22 / 28
页数：7
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