Spectrophotometric method for the determination of amorolfine

被引:0
|
作者
Aparna, A. [1 ]
Anupama, B. [1 ]
Vindya, G. [1 ]
Rao, G. Devala [1 ]
机构
[1] KVSR Siddhartha Coll Pharmaceut Sci, Siddhartha Nagar 520010, Vijayawada, India
关键词
Spectrophotometry; Amorolfine; pharmaceutical dosage form;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Two simple and sensitive spectrophotometric methods have been developed for the estimation of Amorolfine (AMF) in pure and pharmaceutical dosage forms. Method A is based on oxidative coupling of the drug with 3-methyl 2-benzothiazolinone hydrazone(MBTH lambda max 660 nm). The absorbance of the colored species is measured against the corresponding reagent blank. Method B is based on oxidation followed by complex formation when the drug reacts with ferric chloride and 1,10-phenanthroline (lambda max 510nm). These methods have been statistically evaluated and found to be precise and accurate.
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页码:1207 / 1209
页数:3
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