EFFECTS OF AMPHETAMINE ON T-CELL IMMUNE-RESPONSE IN MICE

被引：35
|
作者：
FREIREGARABAL, M
BALBOA, JL
NUNEZ, MJ
CASTANO, MT
LLOVO, JB
FERNANDEZRIAL, JC
BELMONTE, A
机构：
[1] Department of Pharmacology. School, Medicine. University of Santiago de Compostela. Spain
来源：
LIFE SCIENCES | 1991年 / 49卷 / 16期
关键词：
D O I：
10.1016/0024-3205(91)90570-2
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Mice chronically injected with amphetamine (0.4 mg/kg/day) showed a reduction in thymus and spleen cellularity, and in peripheral T lymphocyte population. The blastogenic response of spleen lymphoid cells was assessed and amphetamine was found to inhibit T-cell proliferation. Amphetamine also reduced the capacity of mice to the development and passive transfer of immunity to Listeria monocytogenes.
引用
收藏
页码：PL107 / PL112
页数：6
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