SIGNAL-TRANSDUCTION MECHANISMS IN MESENCHYMAL CELLS

被引：6
|
作者：
MCALLISTER, BS
WALTERS, JD
OLSON, MS
机构：
[1] Department of Periodontology, Oregon Health Sciences University, Portland, OR 97201-3097
来源：
CRITICAL REVIEWS IN ORAL BIOLOGY AND MEDICINE | 1994年 / 5卷 / 3-4期
关键词：
PHOSPHOLIPASE; PROTEIN KINASE; RECEPTORS; GROWTH FACTORS; INFLAMMATORY MEDIATORS; BONE MORPHOGENETIC PROTEINS (BMP);
D O I：
10.1177/10454411940050030501
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Mesenchymal cells are continually stimulated by a wide spectrum of biological mediators. These mediators bind to receptors on the cell surface and initiate a cascade of signaling events. The initial signal transduction pathways known to be stimulated in mesenchymal cells include phospholipase C, phospholipase D, phospholipase A(2), adenylate cyclase, receptor tyrosine kinases, and receptor serine/threonine kinases. These pathways are reviewed and specific applications for therapeutic intervention in wound healing and regenerative therapy in the periodontium are discussed.
引用
收藏
页码：291 / 310
页数：20
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