Metabolic bone disease of prematurity

被引:116
|
作者
Rustico, Stacy E. [1 ,3 ]
Calabria, Andrew C. [1 ,3 ]
Garber, Samuel J. [2 ,3 ]
机构
[1] Childrens Hosp Philadelphia, Div Endocrinol & Diabet, 34th St & Civic Ctr Blvd, Philadelphia, PA 19104 USA
[2] Childrens Hosp Philadelphia, Penn Hosp, Div Neonatol, Philadelphia, PA 19107 USA
[3] Univ Penn, Perelman Sch Med, Dept Pediat, Philadelphia, PA 19104 USA
关键词
Metabolic bone disease; Prematurity; Osteopenia; Rickets;
D O I
10.1016/j.jcte.2014.06.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Metabolic bone disease (MBD) of prematurity remains a significant problem for preterm, chronically ill neonates. The definition and recommendations for screening and treatment of MBD vary in the literature. A recent American Academy of Pediatrics Consensus Statement may help close the gap in institutional variation, but evidence based practice guidelines remain obscure due to lack of normative data and clinical trials for preterm infants. This review highlights mineral homeostasis physiology, current recommendations in screening and monitoring, prevention and treatment strategies, and an added perspective of a bone health team serving a high volume referral neonatal intensive care center. (C) 2014 The Authors. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:85 / 91
页数:7
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