INFLUENCE OF ETHANOL ON THE SALSOLINOL EXCRETION IN HEALTHY-SUBJECTS

被引：6
|
作者：
HABER, H [1 ]
PUTSCHER, I [1 ]
GEORGI, M [1 ]
MELZIG, MF [1 ]
机构：
[1] RES INST MOLEC PHARMACOL,D-10315 BERLIN,GERMANY
来源：
ALCOHOL | 1995年 / 12卷 / 04期
关键词：
SALSOLINOL; URINARY SALSOLINOL; ETHANOL; CAPILLARY GAS CHROMATOGRAPHY-MASS SPECTROMETRY; TETRAHYDROISOQUINOLINES;
D O I：
10.1016/0741-8329(95)00001-8
中图分类号：
R194 [卫生标准、卫生检查、医药管理];
学科分类号：
摘要：
This report describes the change of salsolinol (SAL) levels in the urine of healthy subjects after ethanol ingestion. A new rapid method for SAL extraction from urine sample and a GC-MS assay were used to study the urinary SAL excretion in a group of adult males (n = 14) and females (n = 13) with and without ingestion of ethanol. The results of this study show that the urinary SAL output of all subjects is significantly influenced by the intake of ethanol. A decrease in the SAL level was found in the urine of most of the volunteers (n = 17), whereas only eight subjects showed an increase in the SAL level after administration of ethanol.
引用
收藏
页码：299 / 303
页数：5
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