Recent advances in capillary scale ion chromatography technology

Ion chromatography IC has been a well-established technique for the analysis of ionic samples. The aqueous solution used for IC eluent is well suited for bioanalysis in relative to common liquid chromatography. This is especially true for capillary ion chromatography CIC due to its advantage of small sample needed. CIC is generally divided into three categories including open tubular packed and monolithic. In this review the recent progress of CIC is summarized based on the development of several key components associated with packed column-based system. The development of open tubular ion chromatography is also reviewed.