Recent progress in multi-stage mass spectrometry-based quantitative proteomics

被引：1
|
作者：
Zhang Ying
Yang Pengyuan
Lu Haojie [1 ]
机构：
[1] Fudan Univ, Dept Chem, Shanghai 200032, Peoples R China
来源：
CHINESE JOURNAL OF CHROMATOGRAPHY | 2013年 / 31卷 / 06期
关键词：
proteomics; mass spectrometry (MS); quantitative; review;
D O I：
10.3724/SP.J.1123.2013.03056
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
With the development of proteome research, quantitative proteomics is becoming a very active area of proteomics research. The development of quantitative proteomics requires the advancement of a number of mass spectrometry (MS)-based quantitative techniques. According to the mass spectrometric stage at which the peptides are quantified. MS-based quantitative methods can be divided into two categories: MS-based quantitation and MSn-based quantitation. In this review, the progress of MSn-based quantitation approaches is summarized and the advantages and disadvantages are compared. The trend of MSn-based quantitation is also prospected.
引用
收藏
页码：503 / 509
页数：7
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