The present paper has been planned to examine the India's foreign trade with its major trading partners under the Post-WTO regime. For this purpose, time series data has been used. The data on India's exports and imports to its major trading partners have been taken from the period 1994-95 to 2010-11. It is apparent from the analysis that India's foreign trade has registered a wavering trend under the reference period. The study found that the destination pattern of Indian trade has changed during the Post-WTO period. In other words, Indian foreign trade have reached to new areas of international market, as a result ofwhich geographic base has expanded during the period under study. Examining the India's foreign trade with her major trading partners (namely, United Arab Emirates (UAE); China; United States of America (USA); Saudi Arabia; European Union (EU); Switzerland; Singapore; Australia; Iran; and Hong Kong), we observed that India's trade with its major trading partners has been grown under the study period but at differential rates. The study found that the countries like European Union, UAE, USA, Saudi Arabia and China has accounted for more than 50 per cent of India's total exports and imports under the WTO regime. On the basis of analysis, the study recommended that India must concentrate on the markets like Germany, Italy, U. K, Spain, and Netherlands where intra union imports are relatively of lesser magnitude. In order to improve India's trade with EU, the study suggested the certain recommendations like promoting co-operation on standards, encouraging technology, absorption and undertaking aggressive marketing should be adopted by Indian industries to enhance their exports to the European Union.