Epidemiologic characteristics and outcomes of renal transplantation in hospitals affiliated to Kermanshah University of Medical Sciences, Kermanshah, Iran: 1989-2015

Background and Objective: Renal transplantation outcomes are affected by variables including age and gender of recipient and donor, tissue matching, background conditions, health status before transplantation, comorbidities of recipients, surgeon's experience and expertise, and nature and extensiveness of imrnunosuppressive therapy. The objective of this study was to investigate the effective factors and outcomes of renal transplantation in patients who received this therapy in Kermanshah University affiliated hospitals from 1989 to 2015. Methods: This multi-center study included medical records of all patients who received renal transplantation during the study period. The data were analyzed using SPSS software (ver. 19.0). Central and dispersion indices were used to express continuous variables. The categorical data were reported using frequency and percentage. The chi-squared test and independent t test were used to analyze data. Results: The most common cause of chronic kidney disease was glonnerulonephritis (42.1%). About 0.2% was due to Sport Supplemental Products. The highest number of kidney rejection was documented in the first 6 months after transplantation (10.06%). There was no significant difference between age groups (P=0.15) and gender (P=0.12) regarding survival of the recipients. Conclusion: Despite improvement regarding irreversible transplanted kidney rejection compared to previous studies in the studied centers, the outcomes in particular at the first 6-month period is not satisfactory. Also. mortality rate was higher in comparison to other reports.