Morbidity and mortality after hepatic resection in the modern era

Background/Aims: The purpose of this study was to clarify the risk factors associated with complications following hepatic resections and discuss the appropriate types of perioperative management. Materials and Methods: A retrospective analysis was made of the complications in 355 patients undergoing hepatic resection between April 1985 and August 1992 at the Second Department of Surgery, Kyushu University Hospital. The patients were placed in. true groups according to the occurrence of compications: patients with morbidity and/or mortality (187 patients); patients without either morbidity or mortality (168 patients). Results: The leading complications were the accumulation of fluid in the abdominal and pleural cavities along with septic complications. The only significant factor affecting morbidity and mortality among the preoperative medical conditions was the presence of diabetes while, in addition, the patients with morbidity and/or mortality had higher levels of perioperative transaminase and serum creatinine as compared with those in patients without either morbidity or mortality. Conclusions: The perioperative strategies for reducing morbidity include the strict control of diabetes to reduce septic complications as well as preserve renal function, which can protect against the refractory accumulation, of fluid in, the peritoneal and pleural cavities.