REFERENCE VALUES FOR SERUM AND URINARY URIC-ACID IN CHILDREN

We report on reference values for serum uric acid and urinary uric acid in 361 children under regular diet from our population between 3 to 14 year of age. We found that the serum and urinary uric acid increase through childhood. Urinary uric acid decrease with age when expressed as mg/kg body and bsa ratios and so was the clearance and the uric acid/creatinine ratio in isolated micturition. The serum uric acid values, were scantly smaller to those already reported in our country but the urine uric acid values were similar. The main factors that make different these results were diet, uric acid analytical method used and the number of children studied. The uric acid clearance values were slightly higher than those of Stapleton (1978). We recommend to express uric acid urinary excretion as mg/24h/1,73 m2 and ml/min/1,73 m2 because they minimize the variations with growth. The reference values are expressed in age groups.