EUKARYOTIC DNA-REPLICATION

被引:17
|
作者
WANG, TA [1 ]
LI, JJ [1 ]
机构
[1] UNIV CALIF SAN FRANCISCO,DEPT MICROBIOL,SAN FRANCISCO,CA 94143
关键词
D O I
10.1016/0955-0674(95)80098-0
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Recent discoveries suggest that the initiation of eukaryotic DNA replication involves at least two steps - one occuring near the completion of mitosis and the other at the onset of S phase - that bring about the ordered assembly of initiator proteins at the origin. The identification and characterization of components involved in promoting or antagonizing each of these steps has provided a preliminary understanding of how replication initiation is regulated so precisely during the cell cycle.
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页码:414 / 461
页数:48
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