THYROID AUTOIMMUNITY

被引：18
|
作者：
CHAMPION, BR
COOKE, A
RAYNER, DC
机构：
[1] UNIV ALBERTA,DEPT PATHOL,EDMONTON T6G 2R7,ALBERTA,CANADA
[2] UNIV CAMBRIDGE,DEPT PATHOL,DIV IMMUNOL,CAMBRIDGE CB2 1QP,ENGLAND
来源：
CURRENT OPINION IN IMMUNOLOGY | 1992年 / 4卷 / 06期
关键词：
D O I：
10.1016/0952-7915(92)90060-R
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Antigenic structure remains a major focus in thyroid immunology. The genes for three major thyroid antigens-thyroglobulin, thyroid peroxidase and the thyrotropin receptor-were sequenced in the late 1980's, and epitopes for antibody and T cells have been reported within the last year. In addition, new evidence for selective use of T-cell receptor V gene segments in human thyroid infiltrates may point the way to specific immunotherapy.
引用
收藏
页码：770 / 778
页数：9
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