Pure Small Cell Carcinoma of the Prostate: A Case Report and Literature Review

被引:15
|
作者
Capizzello, Antonio [1 ]
Peponi, Evangelia [1 ]
Simou, Nafsika [2 ]
Ntaskagiannis, Dimitrios [1 ]
Tasiou, Ifigenia [1 ]
Kamina, Sevasti [2 ]
Tsekeris, Periklis [1 ]
机构
[1] Univ Hosp Ioannina, Radiat Therapy Dept, GR-45500 Ioannina, Greece
[2] Univ Hosp Ioannina, Pathol Dept, Ioannina, Greece
来源
CASE REPORTS IN ONCOLOGY | 2011年 / 4卷 / 01期
关键词
Prostate cancer; Small cell carcinoma; Neuroendocrine differentiation;
D O I
10.1159/000324717
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
/Primary small cell carcinoma of the prostate (SCPCa) is a rare pathologic entity with unique clinical features and a poor prognosis. We present a case of a patient diagnosed with pure SCPCa treated with a combined chemo-radiotherapeutic approach. Pathological findings showed that the neoplastic cells exhibited positivity for pancytokeratin, synaptophysin, thyroid transcription factor-1 and CD56. Immunostaining for prostate-specific antigen was negative, while serum prostate-specific antigen was within normal limits. We review the available literature to gain additional information about diagnosis, treatment and prognosis of pure SCPCa.
引用
收藏
页码:88 / 95
页数:8
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