THE SPECIFICITY OF ANTI-HCV SUPPLEMENTARY ASSAYS

被引：12
|
作者：
KITCHEN, AD
TUCKER, NV
机构：
[1] Department of Microbiology, Brentwood Blood Transfusion Centre, Brentwood
来源：
VOX SANGUINIS | 1995年 / 69卷 / 02期
关键词：
D O I：
10.1111/j.1423-0410.1995.tb01677.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A total of 920 samples from blood donors screened as anti-HCV negative by two third-generation screening assays (Ortho Diagnostics v3.0 and Murex Diagnostics VK48) were tested by two supplementary anti-HCV assays, RIBA III (Ortho Diagnostics) and Western blot (Murex Diagnostics VK68). Six (0.65%) of the samples gave scorable bands by RIBA III and 5 (0.54%) by Western blot. Only single-band reactivity was seen and there was no consensus reactivity between the two assays. Single-band reactivity in supplementary assays, especially in samples from low-risk populations, needs to be interpreted with care before being taken as indication of genuine previous or current HCV infection.
引用
收藏
页码：100 / 103
页数：4
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