CHANGES IN GLUCOSE-METABOLISM IN DEMENTIA OF THE ALZHEIMER TYPE COMPARED WITH DEPRESSION - A PRELIMINARY-REPORT

被引：23
|
作者：
GUZE, BH
BAXTER, LR
SCHWARTZ, JM
SZUBA, MP
MAZZIOTTA, JC
PHELPS, ME
机构：
来源：
PSYCHIATRY RESEARCH-NEUROIMAGING | 1991年 / 40卷 / 03期
关键词：
POSITRON EMISSION TOMOGRAPHY; ALZHEIMERS DISEASE; AFFECTIVE DISORDER;
D O I：
10.1016/0165-1781(91)90158-L
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We evaluated positron emission tomography (PET) in the differential diagnosis of depression and Alzheimer's disease. The local cerebral metabolic rate for glucose (LCMRGlc) in the parahippocampal gyrus-hippocampus and the dorsolateral prefrontal cortex were determined. The ratio of the LCMRGlc in those two regions was examined in patients with unipolar depression, bipolar depression, and Alzheimer's dementia. An analysis of variance revealed significant overall intergroup differences in values for both hemispheres. Student's t test showed significant differences in LCMRGlc for both unipolar and bipolar depression as compared with Alzheimer's dementia. These data indicate that PET may be useful in the differential diagnosis of dementia vs. depression.
引用
收藏
页码：195 / 202
页数：8
相关论文
共 50 条
  • [1] GLUCOSE-METABOLISM AS THE SITE OF THE PRIMARY ABNORMALITY IN EARLY ONSET DEMENTIA OF ALZHEIMER TYPE - COMPARISON WITH LATE ONSET DEMENTIA OF ALZHEIMER TYPE
    HOYER, S
    [J]. AGE, 1987, 10 (03): : 109 - 109
  • [2] DIFFERENCES OF REGIONAL CEREBRAL GLUCOSE-METABOLISM BETWEEN PRESENILE AND SENILE DEMENTIA OF ALZHEIMER TYPE
    MIELKE, R
    HERHOLZ, K
    GROND, M
    KESSLER, J
    HEISS, WD
    [J]. NEUROBIOLOGY OF AGING, 1992, 13 (01) : 93 - 98
  • [3] GLUCOSE-METABOLISM AS THE SITE OF THE PRIMARY ABNORMALITY IN EARLY-ONSET DEMENTIA OF ALZHEIMER TYPE
    HOYER, S
    OESTERREICH, K
    WAGNER, O
    [J]. JOURNAL OF NEUROLOGY, 1988, 235 (03) : 143 - 148
  • [4] PRELIMINARY-REPORT ON AFFECTIVE SYMPTOMS IN THE EARLY STAGES OF SENILE DEMENTIA OF THE ALZHEIMER TYPE
    KNESEVICH, JW
    MARTIN, RL
    BERG, L
    DANZIGER, W
    [J]. AMERICAN JOURNAL OF PSYCHIATRY, 1983, 140 (02): : 233 - 235
  • [5] DRAWING PERFORMANCE IN ALZHEIMER-TYPE DEMENTIA (ATD) AND ITS RELATIONSHIP TO BRAIN GLUCOSE-METABOLISM
    OBER, BA
    KOSS, E
    DELIS, DC
    JAGUST, WJ
    FRIEDLAND, RP
    [J]. JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY, 1987, 9 (01) : 69 - 70
  • [6] GLUCOSE-METABOLISM IN UNIPOLAR DEPRESSION
    WRIGHT, JH
    JACISIN, JJ
    RADIN, NS
    BELL, RA
    [J]. BRITISH JOURNAL OF PSYCHIATRY, 1978, 132 (APR) : 386 - 393
  • [7] TOPOGRAPHICAL ANALYSIS OF GLUCOSE-METABOLISM, AS MEASURED WITH POSITRON EMISSION TOMOGRAPHY, IN DEMENTIA OF THE ALZHEIMER TYPE - USE OF LINEAR HISTOGRAMS
    MCNAMARA, D
    HORWITZ, B
    GRADY, CL
    RAPOPORT, SI
    [J]. INTERNATIONAL JOURNAL OF NEUROSCIENCE, 1987, 36 (1-2) : 89 - 97
  • [8] CORTICAL GLUCOSE-METABOLISM AND CLINICAL DEPRESSION
    MORRIS, PLP
    [J]. AMERICAN JOURNAL OF PSYCHIATRY, 1991, 148 (08): : 1103 - 1103
  • [9] Delusions of theft in dementia of the Alzheimer type: A preliminary report
    Hwang, JP
    Yang, CH
    Tsai, SJ
    Liu, KM
    [J]. ALZHEIMER DISEASE & ASSOCIATED DISORDERS, 1997, 11 (02): : 110 - 112
  • [10] CHANGES IN MUSCLE GLUCOSE-METABOLISM IN TYPE-1 DIABETES
    KOIVISTO, VA
    YKIJARVINEN, H
    [J]. ANNALS OF MEDICINE, 1990, 22 (03) : 201 - 205
12345