STUDIES ON THE PHENOTYPE AND KARYOTYPE OF IMMORTALIZED RABBIT KIDNEY EPITHELIAL-CELL LINES

被引：10
|
作者：
MACDONALD, C [1 ]
WATTS, P [1 ]
STUART, B [1 ]
KREUZBURGDUFFY, U [1 ]
SCOTT, DM [1 ]
KINNE, RKH [1 ]
机构：
[1] MAX PLANCK INST SYST PHYSIOL,W-4600 DORTMUND,GERMANY
来源：
EXPERIMENTAL CELL RESEARCH | 1991年 / 195卷 / 02期
关键词：
D O I：
10.1016/0014-4827(91)90396-C
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Differentiated mammalian cell lines can be isolated by immortalizing primary cells by transfection with DNA from plasmids containing sequences from SV40 early region. These cell lines show cytogenetic abnormalities but the degree of aneuploidy is considerably less than that observed in other established cell lines. No correlation was observed between the degree of differentiation of a clone and the extent of chromosomal damage. © 1991.
引用
收藏
页码：458 / 461
页数：4
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