PECULIARITIES OF PARAMETERS OF ECHOCARDIOGRAPHY IN PATIENTS WITH ACUTE CORONARY SYNDROMES WITH COMORBID ANXIETY AND DEPRESSIVE DISORDERS

This study has assessed the functional parameters of the cardiovascular system by echocardiography in patients with acute coronary syndrome (ACS) in combination with anxiety and depressive disorders (ADD). Were examined 152 patients in the first 24 hours after the onset of ACS. All patients in the first 48 hours after hospitalization was performed transthoracic echocardiography (EchoCG) on the apparatus Vivid E9 (General Electric, USA). These echocardiographic indices were analyzed: stroke volume (SV) of left ventricular (LV), minute volume of heart (MVH), ejection fraction (EF), determined by the method Teicholz, end-systolic volume (ESV), end-diastolic volume (EDV), thickness of interventricular septum in diastole (TISD), thickness of posterior wall the LV in diastole (TPWLD), anteroposterior size of the left atrium (LA). Local contractility of LV assessed by the presence of hypo-or akinesia and dyskinesia zones. Diastolic function of LV was assessed by transmitral blood Dopplerograms, noted the presence of valvular cardiac pathology. In the first 72 hours after being transferred from emergency rooms all patients were tested of test of Spielberg-Hanin, Hospital Anxiety and Depression Scale, Beck questionnaire and depression scale epidemiological studies Center USA for determine the presence or not ADD. A result of study patients with ACS in conjunction with ADD have significant excess volume indices of LV in comparison with patients without ADD, in addition, this group have an increase in the size of the LA, MVH and left ventricular has hypertrophy in terms TISD comparison with the group. According to data EchoCG in patients with ACS and ADD very often visualized local contractility disturbances LV, zone of dyskinesia and defeat sclerotic of the aortic and mitral valves and diastolic dysfunction of LV in the type "slow relaxation" in comparison with patients with ACS without ADD. In patients with ACS concomitant ADD has a negative effect on the functional parameters of the cardiovascular system, which may be one of the reasons for unfavorable prognosis in these patients.