EVALUATION OF THE SAFETY OF TARA GUM AS A FOOD INGREDIENT - A REVIEW OF THE LITERATURE

被引:0
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作者
BORZELLECA, JF [1 ]
LADU, BN [1 ]
SENTI, FR [1 ]
EGLE, JL [1 ]
机构
[1] UNIV MICHIGAN,SCH MED,DEPT PHARMACOL,ANN ARBOR,MI 48104
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中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Tara gum is a potential replacement for locust bean gum for use as a formulation aid, stabilizer, and thickener for food applications. In addition to biochemical and digestibility data, studies assessing the toxicity of tara gum are reviewed. The latter includes three 90-day feeding studies, two in rats and one in dogs; two 2-year feeding studies in rats and one in mice; a 3-generation reproduction study with rats and a reproductive toxicity and teratogenicity study with rats; an Ames reverse mutation assay with five Salmonella typhimurium strains; and a micronucleus test in mice. The feeding studies did not indicate any significant adverse effects attributable to tara gum at the maximum dietary level of 5%. The results of the genotoxicity studies were negative. It is concluded that tara gum meets the scientific standards required for classification as a GRAS food ingredient.
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页码:81 / 89
页数:9
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