HEMANGIOMA, SUPRAUMBILICAL MIDLINE RAPHE, AND COARCTATION OF THE AORTA WITH A RIGHT AORTIC-ARCH - SINGLE CAUSAL ENTITY

Most congenital cutaneous hemangiomas are a sporadic occurrence. Hemangiomas have been found in association with coarctation of the aorta and a right aortic arch, A separate association has been noted of mid-line ventral defects with hemangiomas, We report on a patient with multiple hemangiomas, coarctation of the aorta and a right aortic arch, a supraumbilical midabdominal raphe and sternal cleft. Our patient represents an overlap between these two conditions, Review of the literature identified four additional patients with a similar combination of anomalies. The clinical overlap between these 5 patients suggests that they are variants of the same condition and represent a spectrum of defects that includes hemangiomas, midline ventral defects, aortic arch abnormalities and brain malformation. (C) 1995 Wiley-Liss, Inc.