CLIVUS CHORDOMA - A REPORT OF 12 RECENT CASES AND REVIEW OF THE LITERATURE

被引:21
|
作者
HARBOUR, JW [1 ]
LAWTON, MT [1 ]
CRISCUOLO, GR [1 ]
HOLLIDAY, MJ [1 ]
MATTOX, DE [1 ]
LONG, DM [1 ]
机构
[1] JOHNS HOPKINS UNIV HOSP,DEPT OTOLARYNGOL HEAD & NECK SURG,BALTIMORE,MD 21205
来源
SKULL BASE SURGERY | 1991年 / 1卷 / 04期
关键词
D O I
10.1055/s-2008-1057099
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Twelve patients with histologically confirmed clivus chordoma were treated at the Johns Hopkins Hospital between 1971 and 1989. Eight of the patients were men and four were women. The mean age at first operation was 51 years (range, 10 to 80). The most common presenting symptoms were headache, diplopia, dysphagia and dysarthria, and facial sensory changes. Computed tomography, with and without contrast enhancement, proved adequate for tumor identification and localization. Magnetic resonance imaging and angiography were occasionally employed to localize the tumors further and to define tumor vascular supply and proximity to vascular structures. Twenty-two resections were performed in 11 patients, and another patient underwent biopsy only. Seven were also treated with radiation therapy. Tumors recurred in eight patients, six of whom underwent further operations. The mean time to first recurrence was 22 months (range 8 to 36 months). Six of the patients are still alive, with a mean follow-up of 31 months (range, 3 to 89 months) from first surgical resection. The mean survival time from first treatment was 31 months (range, 4 to 62 months) among those patients who died. There was no operative mortality. The 5-year cumulative survival rate was 20%. Six patients with long follow-up have had fair to good results, being free of recurrences for at least a year. However, none of the patients returned to their premorbid baseline of activities. Five of the patients had tumors with the histologic diagnosis of chondroid chordoma. Three of these patients are still alive. The mean age at first treatment was 44 (compared with 62 for typical chordomas). The mean time from symptoms to diagnosis was 29 months (typical chordomas, 18 months). The mean length of survival and time to tumor recurrence were not significantly different between chondroid and typical chordomas.
引用
收藏
页码:200 / 206
页数:7
相关论文
共 50 条
  • [1] Infantile clivus chordoma without clivus involvement: case report and review of the literature
    D. Kombogiorgas
    E. J. St. George
    S. Chapman
    M. English
    G. A. Solanki
    [J]. Child's Nervous System, 2006, 22 : 1369 - 1374
  • [2] Infantile clivus chordoma without clivus involvement: case report and review of the literature
    Kombogiorgas, D.
    George, E. J. St.
    Chapman, S.
    English, M.
    Solanki, G. A.
    [J]. CHILDS NERVOUS SYSTEM, 2006, 22 (10) : 1369 - 1374
  • [3] CHORDOMA OF CLIVUS - A REPORT OF 4 CASES
    PLAUT, HF
    BLATT, ES
    [J]. AMERICAN JOURNAL OF ROENTGENOLOGY RADIUM THERAPY AND NUCLEAR MEDICINE, 1967, 100 (03): : 639 - &
  • [4] Chordoma: a report of six cases and a literature review
    Ben Abdeljelil, N.
    Lahbacha, B.
    Bellalah, A.
    Chabaane, C.
    Hadhri, R.
    Njima, M.
    [J]. VIRCHOWS ARCHIV, 2021, 479 : S301 - S301
  • [5] Metastatic Chordoma: Report of the Two Cases and Review of the Literature
    Rohatgi, Saurabh
    Ramaiya, Nikhil H.
    Jagannathan, Jyothi P.
    Howard, Stephanie A.
    Shinagare, Atul B.
    Krajewski, Katherine M.
    [J]. EURASIAN JOURNAL OF MEDICINE, 2015, 47 (02): : 151 - 154
  • [6] Clivus chordoma, case report
    Choque, R. H. M.
    [J]. HISTOPATHOLOGY, 2010, 57 : 18 - 18
  • [7] DECISIVE ROLE OF IMMUNOCYTOCHEMISTRY IN ASPIRATION CYTOLOGY OF CHORDOMA OF THE CLIVUS - A CASE-REPORT WITH REVIEW OF THE LITERATURE
    GHERARDI, G
    MARVEGGIO, C
    COLA, C
    REDAELLI, G
    [J]. JOURNAL OF LARYNGOLOGY AND OTOLOGY, 1994, 108 (05): : 426 - 430
  • [8] CLIVUS CHORDOMA IN A 9-YEAR-OLD CHILD - CASE-REPORT AND REVIEW OF THE LITERATURE
    FINK, FM
    AUSSERER, B
    SCHROCKSNADEL, W
    PALLUA, AK
    FROMMHOLD, H
    MIKUZ, G
    [J]. PEDIATRIC HEMATOLOGY AND ONCOLOGY, 1987, 4 (02) : 91 - 100
  • [9] Primary intradural chordoma: report on three cases and review of the literature
    Bergmann, M.
    Abdalla, Y.
    Neubauer, U.
    Schildhaus, H. -U.
    Probst-Cousin, S.
    [J]. CLINICAL NEUROPATHOLOGY, 2010, 29 (03) : 169 - 176
  • [10] 2 CASES OF CHORDOMA AND REVIEW OF LITERATURE
    RAO, KVC
    REDDY, CP
    SUNDARESWAR, B
    SAROJINI, C
    REDDY, CRRM
    [J]. CLINICIAN, 1978, 42 (03): : 95 - 100