THE STEROIDOGENIC RESPONSE TO ANGIOTENSIN-II IN THE AUSTRALIAN LUNGFISH, NEOCERATODUS-FORSTERI

Corticosterone, aldosterone and cortisol were found to be present in lungfish plasma. Plasma levels of these hormones were measured in lungfish following separate single intramuscular injections of three forms of angiotensin II; [Asp(1), Ile(5)], [Asp(1), Val(5)] and [Asn(1), Val(5)]. Aldosterone levels were significantly elevated in response to [Asp(1), Ile(5)] AII and [Asn(1), Val(5)] AII injection. [Asp(1) Val(5)] AII increased plasma corticosterone levels. The difference between these data and the negative results previously reported by Blair-West et al. (1977) are discussed.