Prevalence, correlative and statistical relationships of renal dysfunction in patients with chronic ischemic heart failure

The purpose of the study was to examine the prevalence, correlation and statistical relationships of renal dysfunction with functional class, age and gender of patients with coronary heart disease and heart failure. Medical cards of 344 patients (286 men and 58 women) with ischemic chronic heart failure, mean age 59.2 Alpha +/- 9.4 years were analyzed. Total number of patients with chronic renal dysfunction (GFR less than 90 ml/min/1.73 m(2)) was 269 (78.2%). Decreased GFR less than 60 ml/min/1.73 m2 was detected in 43 (12.5%) patients with CHF. In 60% patients up to 45 years, 74.5% from 45 to 59 years, 83.4% aged 60 to 75 years and in 91.7 % of patients aged over 75 years chronic renal dysfunction was diagnosed. Ischemic heart failure, associated with GFR less than 60 ml/min/1.73 m2 was more common in men (12.9% vs 10.3%,X-2=0.3, p=0.58). Correlation analysis showed sustained statistically significant association between eGFR and age (r=-0,34, p<0,001), FC and CHF (r=-0,21, p<0,001). Thus, ischemic heart failure characterized by reduced filtration capacity of the kidneys and is inversely related to age and functional class.