GLYCOSAMINOGLYCANS IN THE SYNOVIAL-FLUIDS OF PATIENTS WITH JUVENILE RHEUMATOID-ARTHRITIS

被引：0
|
作者：
SPELLING, PF [1 ]
HEISE, N [1 ]
TOLEDO, OMS [1 ]
机构：
[1] UNIV SAO PAULO,FAC MED,SCH MED,DEPT RHEUMATOL,DISCIPLINA REUMATOL,AV DR ARNALDO 455,BR-01246 SAO PAULO,BRAZIL
来源：
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY | 1991年 / 9卷 / 02期
关键词：
HYALURONIC ACID; CHONDROITIN SULFATE; SYNOVIAL FLUID; JUVENILE RHEUMATOID ARTHRITIS;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A simple method was used to isolate hyaluronic acid (HA) and sulfated glycosaminoglycans from synovial fluids obtained from children with juvenile rheumatoid arthritis (JRA) and from normal age-matched controls. The bulk of the glycosaminoglycans present in both normal and pathologic synovial fluids consisted of hyaluronic acid and chondroitin 6-sulfate. The diseased synovial fluids showed a sharp decrease in the concentration of glycosaminoglycans when compared with normal controls. These findings are similar to those reported for the synovial fluid of adult patients with rheumatoid arthritis.
引用
收藏
页码：195 / 199
页数：5
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