SIGNIFICANCE OF CAPILLARY BASEMENT-MEMBRANE CHANGES IN DIABETES-MELLITUS

被引：8
|
作者：
BOYD, RB
BURKE, JP
ATKIN, J
THOMPSON, VW
NUGENT, JF
机构：
来源：
JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION | 1990年 / 80卷 / 06期
关键词：
D O I：
10.7547/87507315-80-6-307
中图分类号：
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];
学科分类号：
摘要：
Diabetes mellitus is a disease in which the capillary basement membranes are substantially altered. This diabetic microangiopathy is characterized by a thickening of the basement membrane and changes in its permeability characteristic due to a disturbance in the production and distribution of its functional components. Glucose metabolism and insulin imbalance have been implicated in these basement membrane modifications. The authors describe normal capillary basement membrane architecture and then discuss how pathologic changes caused by diabetes mellitus are related to diabetic foot pathology.
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收藏
页码：307 / 313
页数：7
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