INDUCTION OF ORNITHINE DECARBOXYLASE BY SUBSEIZURE STIMULATION IN THE HIPPOCAMPUS INVIVO

被引：18

作者：

ARAI, A ^{[1
]}

BAUDRY, M ^{[1
]}

STAUBLI, U ^{[1
]}

LYNCH, G ^{[1
]}

GALL, C ^{[1
]}

机构：

[1] UNIV CALIF IRVINE, DEPT ANAT & NEUROBIOL, IRVINE, CA 92717 USA

来源：

MOLECULAR BRAIN RESEARCH | 1990年 / 7卷 / 02期

关键词：

Hippocampus; Ornithine decarboxylase; Seizure;

D O I：

10.1016/0169-328X(90)90094-T

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Electrical stimulation of the Schaffer-collateral axonal system under conditions which do not elicit detectable seizure activity causes an increase in the activity of ornithine decarboxylase (ODC), the rate limiting enzyme of polyamine synthesis, in the hippocampus, olfactory cortex, neocortex and olfactory bulb. The degree of ODC activation is dependent upon the stimulus parameters. The results support the hypothesis that neuronal activity regulates hippocampal polyamine concentrations. © 1990.

引用

页码：167 / 169

页数：3

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