2-ACETYLPYRIDINE THIOCARBONOHYDRAZONES - POTENT INACTIVATORS OF HERPES-SIMPLEX VIRUS RIBONUCLEOTIDE REDUCTASE

被引：0
|
作者：
BLUMENKOPF, TA
HARRINGTON, JA
KOBLE, CS
BANKSTON, DD
MORRISON, RW
BIGHAM, EC
STYLES, VL
SPECTOR, T
机构：
[1] BURROUGHS WELLCOME CO,WELLCOME RES LABS,DIV ORGAN CHEM,RES TRIANGLE PK,NC 27709
[2] BURROUGHS WELLCOME CO,WELLCOME RES LABS,DIV EXPTL THERAPY,RES TRIANGLE PK,NC 27709
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 1992年 / 203卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：20 / MEDI
相关论文
共 50 条
  • [1] 2-ACETYLPYRIDINE THIOCARBONOHYDRAZONES - POTENT INACTIVATORS OF HERPES-SIMPLEX VIRUS RIBONUCLEOTIDE REDUCTASE
    BLUMENKOPF, TA
    HARRINGTON, JA
    KOBLE, CS
    BANKSTON, DD
    MORRISON, RW
    BIGHAM, EC
    STYLES, VL
    SPECTOR, T
    JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (12) : 2306 - 2314
  • [2] EFFECT OF 2-ACETYLPYRIDINE THIOSEMICARBAZONE ON HOST RANGE MUTANTS OF HERPES-SIMPLEX VIRUS TYPE-1 LACKING RIBONUCLEOTIDE REDUCTASE-ACTIVITY
    TURK, SR
    SHIPMAN, C
    GOLDSTEIN, DJ
    WELLER, SK
    ANTIVIRAL RESEARCH, 1988, 9 (1-2) : 156 - 156
  • [3] SELECTIVE-INHIBITION OF HERPES-SIMPLEX VIRUS RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE BY DERIVATIVES OF 2-ACETYLPYRIDINE THIOSEMICARBAZONE
    TURK, SR
    SHIPMAN, C
    DRACH, JC
    BIOCHEMICAL PHARMACOLOGY, 1986, 35 (09) : 1539 - 1545
  • [4] INACTIVATORS OF HERPES-SIMPLEX VIRUS RIBONUCLEOTIDE REDUCTASE - HEMATOLOGICAL PROFILES AND INVIVO POTENTIATION OF THE ANTIVIRAL ACTIVITY OF ACYCLOVIR
    SPECTOR, T
    LOBE, DC
    ELLIS, MN
    BLUMENKOPF, TA
    SZCZECH, GM
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1992, 36 (05) : 934 - 937
  • [5] IDENTIFICATION AND SEPARATION OF THE 2 SUBUNITS OF THE HERPES-SIMPLEX VIRUS RIBONUCLEOTIDE REDUCTASE
    BACCHETTI, S
    EVELEGH, MJ
    MUIRHEAD, B
    JOURNAL OF VIROLOGY, 1986, 57 (03) : 1177 - 1181
  • [6] RIBONUCLEOTIDE REDUCTASE OF HERPES-SIMPLEX VIRUS TYPE-2 RESEMBLES THAT OF HERPES-SIMPLEX VIRUS TYPE-1
    AVERETT, DR
    FURMAN, PA
    SPECTOR, T
    JOURNAL OF VIROLOGY, 1984, 52 (03) : 981 - 983
  • [7] ANTI-VIRAL ACTIVITY OF 2-ACETYLPYRIDINE THIOSEMICARBAZONES AGAINST HERPES-SIMPLEX VIRUS
    SHIPMAN, C
    SMITH, SH
    DRACH, JC
    KLAYMAN, DL
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1981, 19 (04) : 682 - 685
  • [8] SUBSTITUTED PENTAPEPTIDES AND HEXAPEPTIDES AS POTENT INHIBITORS OF HERPES-SIMPLEX VIRUS TYPE-2 RIBONUCLEOTIDE REDUCTASE
    CHANG, LL
    HANNAH, J
    ASHTON, WT
    RASMUSSON, GH
    IKELER, TJ
    PATEL, GF
    GARSKY, V
    UNCAPHER, C
    YAMANAKA, G
    MCCLEMENTS, WL
    TOLMAN, RL
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1992, 2 (10) : 1207 - 1212
  • [9] HERPES-SIMPLEX VIRUS RIBONUCLEOTIDE REDUCTASE MUTANTS ARE HYPERSENSITIVE TO ACYCLOVIR
    COEN, DM
    GOLDSTEIN, DJ
    WELLER, SK
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1989, 33 (08) : 1395 - 1399
  • [10] THE HERPES-SIMPLEX VIRUS RIBONUCLEOTIDE REDUCTASE IS REQUIRED FOR OCULAR VIRULENCE
    KINTNER, RL
    BRANDT, CR
    VISALLI, RJ
    PUMFERY, AM
    GRAU, DR
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1991, 32 (04) : 852 - 852
12345