HIGH-CELL-DENSITY CULTIVATION OF ESCHERICHIA-COLI

被引:113
|
作者
RIESENBERG, D [1 ]
机构
[1] INST MICROBIOL & EXPTL THERAPY, W-6900 JENA, GERMANY
关键词
D O I
10.1016/S0958-1669(05)80142-9
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
High-cell-density cultivations of Escherichia coli in glucose-mineral-salt media produce more than 100 g dry cells litre-1 in special fed-batch modes with feeding of glucose and ammonia only. The specific growth rate can be adjusted to allow optimum recombinant protein generation.
引用
收藏
页码:380 / 384
页数:5
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