INVITRO AND INVIVO STUDIES OF 3,4-DIHYDRO-6-[4-(3,4-DIMETHOXYBENZOYL)-1-PIPERAZINYL]-2(1H)-QUINOLINONE (OPC-8212), A NOVEL POSITIVE INOTROPIC DRUG, IN VARIOUS ANIMALS

被引：0

作者：

YAMASHITA, S ^{[1
]}

HOSOKAWA, T ^{[1
]}

KOJIMA, M ^{[1
]}

MORI, T ^{[1
]}

YABUUCHI, Y ^{[1
]}

机构：

[1] OTSUKA PHARMACEUT CO LTD, TOKUSHIMA RES INST, KAGASUNO KAWAUCHI CHO, TOKUSHIMA 77101, JAPAN

来源：

ARZNEIMITTELFORSCHUNG-DRUG RESEARCH | 1984年 / 34-1卷 / 3A期

关键词：

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：342 / 346

页数：5

共 50 条

[1] NEW POSITIVE INOTROPIC AGENT, OPC-8212 (3,4-DIHYDRO-6-[4-(3,4-DIMETHOXYBENZOYL)-1-PIPERAZINYL]-2(1H)-QUINOLINONE) - PREFACE
TAIRA, N
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1984, 34-1 (3A): : 333 - 333
[2] PHYSICOCHEMICAL PROPERTIES AND STABILITIES OF A NEW POSITIVE INOTROPIC AGENT, 3,4-DIHYDRO-6-[4-(3,4-DIMETHOXYBENZOYL)-1-PIPERAZINYL]-2(1H)-QUINOLINONE (OPC-8212)
SHIMIZU, T
OSUMI, T
NIIMI, K
NAKAGAWA, K
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1984, 34-1 (3A): : 334 - 341
[3] EFFECTS OF 3,4-DIHYDRO-6-[4-(3,4-DIMETHOXYBENZOYL)-1-PIPERAZINYL]-2(1H)-QUINOLINONE (OPC-8212), A NEW INOTROPIC AGENT, ON CARDIOTONIC ACTIVITY AND CORONARY HEMODYNAMICS
INOUE, M
HORI, M
NAKAJIMA, S
KITAKAZE, M
FUKUNAMI, M
ISHIDA, Y
ABE, H
ARZNEIMITTELFORSCHUNG-DRUG RESEARCH, 1984, 34-1 (3A): : 355 - +
[4] POSITIVE INOTROPIC EFFECT OF 3,4-DIHYDRO-6-[4-(3,4-DIMETHOXYBENZOYL)-1-PIPERAZINYL]-2(1H)-QUINOLINONE (OPC-8212) AND MECHANISM OF ACTION IN GUINEA-PIG VENTRICULAR MYOCARDIUM
TAKEYA, K
YAJIMA, M
KOBAYASHIANDO, S
ANDO, H
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1984, 34-1 (3A): : 364 - &
[5] METABOLISM OF A NEW POSITIVE INOTROPIC AGENT, 3,4-DIHYDRO-6-[4-(3,4-DIMETHOXYBENZOYL)-1-PIPERAZINYL]-2(1H)-QUINOLINONE (OPC-8212) IN THE RAT, MOUSE, DOG, MONKEY AND HUMAN
MIYAMOTO, G
SASABE, H
TOMINAGA, N
UEGAKI, N
TOMINAGA, M
SHIMIZU, T
XENOBIOTICA, 1988, 18 (10) : 1143 - 1155
[6] ACUTE HEMODYNAMIC-EFFECTS OF A NEW POSITIVE INOTROPIC AGENT, 3,4-DIHYDRO-6-[4-(3,4-DIMETHOXYBENZOYL)-1-PIPERAZINYL]-2(1H)-QUINOLINONE (OPC-8212), IN CONSCIOUS AND ANESTHETIZED DOGS
MIYAZAKI, S
SASAYAMA, S
NAKAMURA, Y
KIHARA, Y
SUSAWA, T
KAWAI, C
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1986, 8 (01) : 14 - 20
[7] THE INHIBITORY EFFECTS OF A POSITIVE INOTROPIC QUINOLINONE DERIVATIVE, 3,4-DIHYDRO-6-[4-(3,4-DIMETHOXYBENZOYL)-1-PIPERAZINYL]-2(1H)-QUINOLINONE (OPC-8212), ON BONE-MARROW PROGENITOR CELLS AND PERIPHERAL LYMPHOCYTES
BUSCH, FW
TILLMANN, A
BECKER, EW
OWSIANOWSKI, M
BERG, PA
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1992, 42 (06) : 629 - 634
[8] PHARMACOKINETICS OF A NEW POSITIVE INOTROPIC AGENT, 3,4-DIHYDRO-6-[4-(3,4-DIMETHOXYBENZOYL)-1-PIPERAZINYL]-2(1H)-QUINOLINONE (OPC-8212), IN THE RAT, RABBIT, BEAGLE DOG AND RHESUS-MONKEY
MIYAMOTO, G
SASABE, H
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1984, 34-1 (3A): : 394 - 403
[9] THE EFFECT OF A NEW POSITIVE INOTROPIC AGENT, 3,4-DIHYDRO-6-[4-(3,4-DIMETHOXYBENZOYL)-1-PIPERAZINYL]-2(1H)-QUINOLINONE (OPC-8212), ON THIN BUNDLES OF SKINNED FIBERS FROM CARDIAC-MUSCLE
ENDO, M
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1984, 34-1 (3A): : 380 - &
[10] EFFECT OF 3,4-DIHYDRO-6-[4-(3,4-DIMETHOXYBENZOYL)-1-PIPERAZINYL]-2(1H)-QUINOLINONE (OPC-8212) ON THE MEMBRANE CURRENTS OF RABBIT SINO-ATRIAL NODE CELLS
SATOH, H
HASHIMOTO, K
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1984, 34-1 (3A): : 376 - &

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