Apathy and Leukoaraiosis in Mild Cognitive Impairment and Alzheimer's Disease: Multicenter Diagnostic Criteria according to the Latest Studies

被引：10
|
作者：
Maria Sarabia-Cobo, Carmen [1 ]
Perez, Victoria [2 ]
Hermosilla, Carmen [2 ]
Jose Nunez, Maria [2 ]
de Lorena, Pablo [2 ]
机构：
[1] Univ Cantabria, Santander, Spain
[2] CR Santa Lucia, Madrid, Spain
来源：
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA | 2014年 / 4卷 / 02期
关键词：
Apathy; Mild cognitive impairment; Alzheimer's disease; Neuroimaging; Predictors; White matter;
D O I：
10.1159/000363227
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Aims: The aim is to study the prevalence and possible relationship of apathy and leukoaraiosis in cases of cognitive impairment of varying severity in Spain. Methods: We conducted a cross-sectional, descriptive, multicenter study involving 109 patients with Alzheimer's disease (AD) and 59 with mild cognitive impairment (MCI). Results: The older group with AD had a higher prevalence of leukoaraiosis and apathy, with significant differences compared to the MCI group. Conclusions: To our knowledge, this is the first multicenter study in our country that jointly analyzes the presence of apathy and leukoaraiosis in the institutionalized elderly with varying degrees of cognitive impairment according to the most recent criteria for detecting apathy in dementia. (C) 2014 S. Karger AG, Basel
引用
收藏
页码：228 / 235
页数：8
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