IMPROVED ENERGY COMPENSATION FOR TIME-OF-FLIGHT MASS-SPECTROMETRY

被引：7
|
作者：
SHORT, RT
TODD, PJ
机构：
[1] Oak Ridge National Laboratory, Oak Ridge, 37831-6365, TN
来源：
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 1994年 / 5卷 / 08期
关键词：
D O I：
10.1016/1044-0305(94)80011-1
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A model for improved energy compensation in time-of-flight (TOF) mass spectrometry has been developed and tested. This model includes effects of both the acceleration and drift region on mass resolution for surface desorption TOF mass spectrometers that employ ion mirrors to improve mass resolution. Appropriate placement of an additional stage onto the conventional one- and two-stage mirrors provides compensation for flight time spreads, caused by initial ion kinetic energy distributions, in both regions. Experimental results that validate the model calculations are presented for a modified commercial two-stage ion mirror. For example, m/DELTAm for Na+ was improved from approximately 100 to approximately 200 using only a 200-eV drift energy and a 58-cm drift path.
引用
收藏
页码：779 / 787
页数：9
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