REPEATED ASPIRATION OF OVARIAN FOLLICLES AND EARLY CORPUS-LUTEUM CYSTS IN AN IN-VITRO FERTILIZATION PROGRAM REDUCES THE RISK OF OVARIAN HYPERSTIMULATION SYNDROME IN HIGH RESPONDERS

被引:13
|
作者
AMIT, A [1 ]
YARON, Y [1 ]
YOVEL, I [1 ]
PEYSER, MR [1 ]
DAVID, MP [1 ]
BOTCHAN, A [1 ]
LESSING, JB [1 ]
机构
[1] TEL AVIV UNIV,SERLIN MATERN HOSP,SACKLER FAC MED,TEL AVIV SOURASKY MED CTR,IL-61070 TEL AVIV,ISRAEL
关键词
IN-VITRO FERTILIZATION; OVARIAN HYPERSTIMULATION SYNDROME; OVULATION INDUCTION; REPEATED ASPIRATION;
D O I
10.1093/oxfordjournals.humrep.a138225
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
A retrospective analysis of ovarian hyperstimulation syndrome in high responders undergoing in-vitro fertilization (IVF) is presented. High responders were defined as having >20 follicles and serum oestradiol >3000 pg/ml after treatment with human menopausal gonadotrophin. Of the initial 30 IVF cycles in high responders, 23 developed a moderate-to-severe ovarian hyperstimulation syndrome (76.7%). Subsequently, 15 other IVF cycles in high responders were combined with a repeated aspiration of ovarian follicles and corpus luteum cysts just prior to embryo transfer. Only three patients (20%) developed a moderate ovarian hyperstimulation syndrome (P = 0.0004). We conclude that repeated follicular aspiration is safe and results in a significant reduction in the incidence and severity of this condition in high responders undergoing IVF.
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页码:1184 / 1186
页数:3
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